monoacylglycerol lipase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T5737	Euphol		Others , Lipase , Endogenous Metabolite
	Euphol, an alcohol tetracyclic triterpene, has a wide range of pharmacological properties and is considered to have anti-inflammatory action.		Others , Lipase , Endogenous Metabolite
T15635	JZP-430		Lipase , MAGL
	JZP-430 is an effective, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50: 44 nM). It also shows ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL...		Lipase , MAGL
T15614	JJKK 048		Lipase
	JJKK 048 is a potent and selective MAGL inhibitor.		Lipase
T8974	ML-211		Others
	ML-211 is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and the related LYPLA2 (IC50 = 30 nM)		Others
T9967	MAGL-IN-5		Lipid
	MAGL-IN-5 is a non-selective lipase inhibitor.		Lipid
T5353	ABX-1431	Elcubragistat	Lipase
	ABX-1431 (Elcubragistat) is a selective and orally available CNS-penetrant monoacylglycerol lipase (MAGL/MGLL) inhibitor (IC50: 14 nM).		Lipase
T9687	MAGL-IN-4	His121 ARG57	Lipase
	MAGL-IN-4 (His121 ARG57) is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases.		Lipase
T15632	JW 642		Lipase
	JW 642 is an effective inhibitor of monoacylglycerol lipase (MAGL) (IC50: 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively).		Lipase
T17260	WWL70		Lipase , MAGL
	WWL70 is a selective alpha/beta hydrolase domain 6 inhibitors (IC50: 70 nM).		Lipase , MAGL
T61294	Monoacylglycerol lipase inhibitor 1
	Monoacylglycerol lipase inhibitor 1, also known as compound 13 [1], is a potent inhibitor of monoacylglycerol lipase.
T4052	KML29		Lipase
	KML29 is highly selective and effective monoacylglycerol lipase (MAGL) inhibitor. It has effective inhibition of human/mouse/rat MAGL (IC50: 5.9/15/43 nM). It has not inhibitory for FAAH (IC50 > 50 μM). It also effective...		Lipase
T5815	MJN110	Cravatt Reagent	Lipase
	MJN110 (Cravatt Reagent) is a potent and selective MAGL inhibitor. Cravatt Reagent inhibits MAGL (IC50 = 9.1 nM). MJN110(Cravatt Reagent) Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model.		Lipase
T2338	JZL195		FAAH , Lipase , Autophagy
	JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.		FAAH , Lipase , Autophagy
T6554	JZL 184	JZL184	Lipase
	JZL 184 is a potent and selective inhibitor of MAGL with IC50 of 8 nM and 4 μM for inhibition of MAGL and FAAH in mouse brain membranes respectively.		Lipase
T8994	ML-226	ML226,ML-226	MAGL
	ML226 is a α/β hydrolase domain-containing protein 11 (ABHD11) inhibitor that inhibits ABHD11 in vitro and in situ.		MAGL
T9374	AA38-3	1-Piperidinecarboxylic acid, 4-nitrophenyl ester	FAAH , Lipase , MAGL
	AA38-3 (1-Piperidinecarboxylic acid, 4-nitrophenyl ester) inhibites three SHs (ABHD6, ABHD11, and FAAH)		FAAH , Lipase , MAGL
T27405	GAT211	GAT-211,AZ-4,GAT 211,AZ 4,AZ4
	GAT211 is a CB1 positive allosteric modulator. GAT211 suppresses allodynia and produces synergistic antiallodynic effects with monoacylglycerol lipase and fatty acid amide hydrolase inhibitors in paclitaxel-treated mice.
T3591	URB602		Lipase , Antibacterial
	URB602 is a specific monoacylglycerol lipase (MGL) inhibitor, which inhibits rat brain MGL (IC50: 28±4 μM) through a noncompetitive mechanism.		Lipase , Antibacterial
T11724	JNJ-42226314		Lipase
	JNJ-42226314 is a highly selective non-covalent monoacylglycerol lipase (MAGL) inhibitor with anti-injury effects.JNJ-42226314 shows efficacy via endogenous cannabinoid-2-acryloylglycerol (2-AG) in models of neuropathic ...		Lipase
T28165	NF-1819	NF 1819,NF1819	Lipase
	NF-1819 is a potent and selective irreversible MGL (β-lactam-based monoacylglycerol lipase) inhibitor. NF-1819 alleviates symptoms in a MS model in vivo and exhibits analgesic effects in an acute inflammatory pain model ...		Lipase